If you've ever worked with powder blends for tablet compression, you know the struggle—poor flow, segregation, and dust are constant headaches. Wet granulation isn't just about sticking particles together; it's a precision engineering process that transforms problematic powders into free-flowing, uniform granules. This guide walks you through the entire wet granulation workflow, from raw material milling and high-shear mixing to fluid bed drying and final lubrication. We'll cut through the theory and focus on the critical control points—binder addition rate, granulation endpoint, and drying curves—that separate a robust process from a failed batch.

Coating machines are now widely used in pharmaceutical industry, food industry, biographical industry and so on. It can coat tablets, pills and sugars with organic film, water-soluble film or sugar coat, which can fulfill controlled or sustained release of drugs. The working principle of coating mac

Traditional capsules can be divided into two types: hard capsules (be filled with powdery medicine) and soft gels (be filled with liquid medicine such as fish oil, Vitamin E and Vitamin A). In recent years, new liquid capsule filling technologies have been developed, such as filling semi-solid or oi

Tablet is a very common and important dosage in pharmaceutical area. The machine to produce tablet is tablet press machine. Here we summarized 4 advises for choosing tablet press machine. Buyers always have four misunderstandings while buying tablet press machine. We wanna reveal these misunderstand

Pellet production, except some special preparing methods, normally consists of four processes: nucleating, agglomeration, overlapping, and migration. Nucleating refers to the process when powder is added into liquid and forms nucleus. The number of nucleus increases as more solid powder and adhesive